Chemoenzymatic and enantiodivergent routes to 1,2-ring-fused bicyclo[2.2.2]octane and related tricyclic frameworks.

نویسندگان

  • Kerrie A B Austin
  • Jon D Elsworth
  • Martin G Banwell
  • Anthony C Willis
چکیده

New and simple protocols are described for the conversion of the enzymatically-derived and enantiomerically pure cis-1,2-dihydrocatechol (X = I) and its 6-methylated derivative into either antipodal form of compounds embodying the tricyclic frameworks of terpenoids . Key steps include intramolecular Diels-Alder (IMDA) and (in some cases) singlet or triplet-based photochemical processes.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 8 4  شماره 

صفحات  -

تاریخ انتشار 2010